Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205464 | 0.89 | L3MBTL1 (0.48) | ACESMN1; SMN2KMT2ANPSR1MEN1 | |
| SCHEMBL9201161 | 0.86 | PPARG (0.51) | SMN1; SMN2KMT2AMEN1POLBMAPT | |
| SCHEMBL6632835 | 0.83 | SMN1; SMN2 (0.54) | ACESMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL6632836 | 0.83 | SMN1; SMN2 (0.54) | ACESMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL4940835 | 0.83 | KMT2A (0.43) | SMN1; SMN2KMT2ANPSR1MEN1POLB | |
| SCHEMBL9208264 | 0.82 | KMT2A (0.47) | SMN1; SMN2KMT2ANPSR1MEN1POLB | |
| SCHEMBL7861410 | 0.80 | L3MBTL1 (0.49) | SMN1; SMN2MAPTPPARGPPARALMNA | |
| SCHEMBL20676110 | 0.79 | SMN1; SMN2 (0.52) | ACESMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7996690 | 0.77 | PPARA (0.57) | ACESMN1; SMN2PPARGPPARALMNA | |
| SCHEMBL1434442 | 0.77 | PPARG (0.54) | ACESMN1; SMN2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423802-B1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMA (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5134154-A | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0423802-A1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-24 | — | — | EP | disclosed |