Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436018 | 1.00 | TDP1 (0.41) | TDP1ALDH1A1MAPTATMHPGD | |
| SCHEMBL10513490 | 1.00 | TDP1 (0.41) | TDP1ALDH1A1MAPTATMHPGD | |
| SCHEMBL10513485 | 1.00 | TDP1 (0.41) | TDP1ALDH1A1MAPTATMHPGD | |
| SCHEMBL9519895 | 0.93 | TDP1 (0.42) | TDP1ALDH1A1MAPTATMHPGD | |
| SCHEMBL9043536 | 0.92 | TDP1 (0.40) | TDP1ALDH1A1MAPTATMHPGD | |
| SCHEMBL9520375 | 0.92 | ALDH1A1 (0.41) | TDP1ALDH1A1MAPTATMHPGD | |
| SCHEMBL9207906 | 0.91 | RAB9A (0.41) | TDP1ALDH1A1MAPTATMHPGD | |
| SCHEMBL9520632 | 0.91 | RAB9A (0.41) | TDP1ALDH1A1MAPTATMHPGD | |
| SCHEMBL7807884 | 0.90 | MMP2 (0.45) | TDP1ALDH1A1MAPTATMHPGD | |
| SCHEMBL9266276 | 0.89 | ALDH1A1 (0.39) | TDP1ALDH1A1MAPTATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |