Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19479525 | 0.77 | CTSK (0.43) | KLK5USP30KMT2ANPC1MEN1 | |
| SCHEMBL15447605 | 0.77 | CTSK (0.43) | KLK5USP30KMT2ANPC1MEN1 | |
| SCHEMBL20142381 | 0.76 | GPR119 (0.52) | GPR119NR1H2NR1H3USP30KDM4E | |
| SCHEMBL21360316 | 0.76 | GPR119 (0.52) | GPR119NR1H2NR1H3USP30KDM4E | |
| SCHEMBL16731904 | 0.76 | GPR119 (0.52) | GPR119NR1H2NR1H3USP30KDM4E | |
| SCHEMBL12324594 | 0.75 | NR1H2 (0.72) | GPR119NR1H2NR1H3KMT2AMEN1 | |
| SCHEMBL21886120 | 0.75 | NR1H2 (0.72) | GPR119NR1H2NR1H3KMT2AMEN1 | |
| SCHEMBL15148025 | 0.75 | NR1H2 (0.72) | GPR119NR1H2NR1H3KMT2AMEN1 | |
| SCHEMBL29035348 | 0.74 | SCN9A (0.48) | KMT2ALTA4H | |
| SCHEMBL26246339 | 0.74 | SCN9A (0.48) | KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090612-C | Amine derivatives of oxo-and hydroxy-substituted hydrocarbons | NARHEX LTD (HK) | 2002-09-11 | — | — | CN | disclosed |
| CN-1100090-A | amine derivatives of oxo-and hydroxy-substituted hydrocarbons | NARHEX LTD (HK) | 1995-03-15 | — | — | CN | disclosed |
| EP-0633881-A4 | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUED HYDROCARBONS. | — | 1995-02-22 | — | — | EP | disclosed |
| EP-0633881-A1 | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUED HYDROCARBONS | Narhex Limited (HK) | 1995-01-18 | — | — | EP | disclosed |