SCHEMBL9207367

SCHEMBL9207367

CCOC(=O)c1nc(C)oc1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 6/20 0.44
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 3/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP1A2 P05177 2/20 0.41
FBP1 P09467 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
PDCD4 Q53EL6 1/20 0.40
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9296032 0.85 TARBP2 (0.43) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL3822718 0.85 ALDH1A1 (0.44) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL2616840 0.80 TARBP2 (0.58) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL3274432 0.80 MAPT (0.47) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL9297041 0.79 HSD17B10 (0.38) ALDH1A1KDM4EHPGDKMT2AHSD17B10
SCHEMBL9296577 0.79 FBP1 (0.42) TARBP2ALDH1A1CYP1A2FBP1HDAC4
SCHEMBL7940493 0.77 TARBP2 (0.48) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL19207030 0.77 TARBP2 (0.49) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL361590 0.77 ALDH1A1 (0.50) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL9207374 0.77 TARBP2 (0.43) TARBP2ALDH1A1KDM4EHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0419944-B1 Oxazole and thiazole carboxylic acid amines BASF AG (DE) 1995-03-15 EP disclosed
US-5284821-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1994-02-08 US disclosed
US-5256633-A Applying pre or postemergence BASF AKTIENGESELLSCHAFT (DE) 1993-10-26 US disclosed
US-5244867-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1993-09-14 US disclosed
EP-0419944-A2 Oxazole and thiazole carboxylic acid amines BASF Aktiengesellschaft (DE) 1991-04-03 EP disclosed