Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 8/20 | 0.49 |
| ▸ | SOD1 | P00441 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204316 | 0.84 | TOP2A (0.52) | KAT2BFLT3SOD1TOP2APOLB | |
| SCHEMBL8421485 | 0.82 | SOD1 (0.51) | FLT3SOD1 | |
| SCHEMBL8421424 | 0.79 | SOD1 (0.56) | SOD1TOP2APOLB | |
| SCHEMBL8421956 | 0.78 | FLT3 (0.57) | FLT3SOD1TOP2APOLB | |
| SCHEMBL8423745 | 0.78 | SOD1 (0.47) | SOD1 | |
| Hydrochloric Acid SCHEMBL8421903 | 0.78 | SOD1 (0.55) | SOD1TOP2APOLB | |
| SCHEMBL9202631 | 0.76 | TOP2A (0.45) | KAT2BFLT3SOD1TOP2AGAA | |
| SCHEMBL15165345 | 0.74 | FLT3 (0.89) | FLT3 | |
| SCHEMBL9203591 | 0.73 | KAT2B (0.51) | KAT2BRCE1POLBGAA | |
| SCHEMBL9208673 | 0.72 | SOD1 (0.56) | SOD1RCE1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497809-B1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-06-28 | — | — | EP | disclosed |
| US-5162320-A | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1992-11-10 | — | — | US | disclosed |
| EP-0497809-A1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES. | BOEHRINGER MANNHEIM ITALIA (IT) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991006540-A1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1991-05-16 | — | — | WO | disclosed |