Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205582 | 0.95 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6LRRK2MEN1 | |
| SCHEMBL9209434 | 0.89 | NR1I2 (0.52) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9210237 | 0.84 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6LRRK2MEN1 | |
| SCHEMBL9212415 | 0.84 | NR1I2 (0.56) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9200228 | 0.83 | NR1I2 (0.40) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705958 | 0.83 | NR1I2 (0.42) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL10413682 | 0.82 | HDAC6 (0.36) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705774 | 0.82 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705948 | 0.82 | NR1I2 (0.43) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9205839 | 0.82 | CYP2C9 (0.47) | NR1I2CYP3A4CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | claimed |
| US-5110821-A | Picornavirus | STERLING DRUG INC. (US) | 1992-05-05 | — | — | US | claimed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | claimed |
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5110821-A | Picornavirus | STERLING DRUG INC. (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |