Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209434 | 0.95 | NR1I2 (0.52) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9205582 | 0.88 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9207573 | 0.84 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9204655 | 0.82 | NR1I2 (0.61) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9201818 | 0.82 | NR1I2 (0.39) | NR1I2CYP3A4CYP2D6MAPK14SCARB1 | |
| SCHEMBL9200266 | 0.79 | NR1I2 (0.73) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9205839 | 0.79 | CYP2C9 (0.47) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9201847 | 0.78 | NR1I2 (0.56) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705716 | 0.78 | NR1I2 (0.53) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8128286 | 0.77 | NR1I2 (0.55) | NR1I2CYP3A4CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110821-A | Picornavirus | STERLING DRUG INC. (US) | 1992-05-05 | — | — | US | claimed |
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5110821-A | Picornavirus | STERLING DRUG INC. (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |