Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201847 | 0.88 | NR1I2 (0.56) | NR1I2CYP3A4CYP2D6ACHEBCHE | |
| SCHEMBL9705958 | 0.85 | NR1I2 (0.42) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705948 | 0.84 | NR1I2 (0.43) | NR1I2CYP3A4CYP2D6MAPTMEN1 | |
| SCHEMBL9207573 | 0.84 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6LRRK2MAPT | |
| SCHEMBL9705774 | 0.84 | NR1I2 (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9200228 | 0.83 | NR1I2 (0.40) | NR1I2CYP3A4CYP2D6MAPTMEN1 | |
| SCHEMBL9204655 | 0.83 | NR1I2 (0.61) | NR1I2CYP3A4CYP2D6ACHEBCHE | |
| SCHEMBL9210194 | 0.83 | NR1I2 (0.53) | NR1I2CYP3A4CYP2D6MAPTMEN1 | |
| SCHEMBL9436214 | 0.82 | NR1I2 (0.43) | NR1I2CYP3A4CYP2D6MAPTMEN1 | |
| SCHEMBL9436119 | 0.81 | PTGS2 (0.40) | NR1I2CYP3A4CYP2D6TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5175178-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4942241-A | PICORNAVIRUS INCLUDING RHINOVIRUS | STERLING DRUG INC. (US) | 1990-07-17 | — | — | US | disclosed |