Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 3/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208720 | 0.95 | ADRB2 (0.57) | ADRB2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9218059 | 0.87 | TOP2A (0.55) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7131518 | 0.84 | ADRB2 (0.59) | ADRB2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9525112 | 0.84 | ADRB2 (0.53) | ADRB2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6776958 | 0.84 | ADRB2 (0.59) | ADRB2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL7131512 | 0.84 | ADRB2 (0.59) | ADRB2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9668175 | 0.83 | ADRB2 (0.60) | ADRB2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10473672 | 0.83 | KCNH2 (0.56) | ADRB2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29492858 | 0.83 | ADRB2 (0.68) | ADRB2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL2844967 | 0.83 | ADRB2 (0.68) | ADRB2KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390215-B1 | Quinolone derivatives and salts thereof, preparation process es thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KK (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5153203-A | QUINOLONE DERIVATIVES AND SALTS THEREOF, PREPARATION PROCESSES THEREOF, AND ANTIBACTERIAL AGENTS CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0390215-A2 | Quinolone derivatives and salts thereof, preparation process es thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-03 | — | — | EP | disclosed |