Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380940 | 0.89 | ALDH1A1 (0.54) | KCNH2KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL9572055 | 0.84 | ADRB2 (0.56) | ADRB2KCNH2KMT2AKDM4EHPGD | |
| SCHEMBL9208068 | 0.84 | ADRB2 (0.55) | ADRB2KCNH2KMT2AKDM4EHPGD | |
| SCHEMBL9208720 | 0.84 | ADRB2 (0.57) | ADRB2KCNH2KMT2AKDM4EHPGD | |
| SCHEMBL10407257 | 0.83 | ADRB2 (0.59) | ADRB2KCNH2KDM4EHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL9572035 | 0.83 | ADRB2 (0.55) | ADRB2KCNH2KMT2AKDM4EHPGD | |
| SCHEMBL9146396 | 0.83 | ADRB2 (0.58) | ADRB2KCNH2KDM4EHPGDALDH1A1 | |
| SCHEMBL7131518 | 0.82 | ADRB2 (0.59) | ADRB2KCNH2KMT2AKDM4EHPGD | |
| SCHEMBL9528034 | 0.82 | ADRB2 (0.54) | ADRB2KCNH2KMT2AKDM4EHPGD | |
| SCHEMBL6776958 | 0.82 | ADRB2 (0.59) | ADRB2KCNH2KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562042-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5137892-A | Bactericides | ABBOTT LABORATORIES (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992010191-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1992-06-25 | — | — | WO | disclosed |