Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 6/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272981 | 0.91 | CYP2C9 (0.43) | MAPK1RPS6KB1CDK2MAPKAPK2GSK3B | |
| SCHEMBL9208318 | 0.85 | MAPK1 (0.36) | MAPK1CDK2MAPTKDM4EMEN1 | |
| SCHEMBL9209236 | 0.76 | SMN1; SMN2 (0.35) | MAPK1CDK2MAPTKDM4EMEN1 | |
| SCHEMBL9208328 | 0.76 | CYP2C9 (0.44) | MAPK1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL9213226 | 0.76 | KDM4E (0.39) | MAPK1MAPTKDM4EMEN1GAA | |
| SCHEMBL9218073 | 0.73 | MAPT (0.65) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6198615 | 0.73 | CDC7 (0.47) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL9219865 | 0.72 | ALDH1A1 (0.32) | MAPK1MAPTKDM4EMEN1GAA | |
| SCHEMBL9218464 | 0.72 | SMN1; SMN2 (0.35) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL6632448 | 0.70 | L3MBTL1 (0.43) | MAPTKDM4EMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |