Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727854 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL9205873 | 0.92 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL10362668 | 0.88 | MMP2 (0.49) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9120900 | 0.88 | HTR2A (0.39) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL9118872 | 0.88 | HTR2A (0.39) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL9118887 | 0.87 | KMT2A (0.39) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL9118882 | 0.87 | KMT2A (0.39) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL9204434 | 0.87 | TDP1 (0.48) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9204969 | 0.87 | TDP1 (0.46) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9728572 | 0.87 | TDP1 (0.48) | ALDH1A1MAPTHPGDTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126587-B1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMA (JP) | 1995-04-19 | — | — | EP | disclosed |