Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204156 | 0.98 | CYP4F2 (0.52) | CYP4F2CYP4A11KMT2AMEN1NPC1 | |
| SCHEMBL4337810 | 0.88 | TRPV1 (0.53) | CYP4F2CYP4A11NPC1RAB9APOLB | |
| SCHEMBL5281907 | 0.86 | CYP4F2 (0.52) | CYP4F2CYP4A11KMT2AMEN1NPC1 | |
| SCHEMBL10762816 | 0.84 | S1PR1 (0.58) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL9114890 | 0.82 | NPSR1 (0.54) | CYP4F2CYP4A11KMT2AMEN1NPC1 | |
| SCHEMBL1028484 | 0.81 | PDK1 (0.56) | NPC1RAB9AMAPTGAALMNA | |
| SCHEMBL8419389 | 0.81 | AOC3 (0.56) | CYP4F2CYP4A11KMT2AMEN1NPC1 | |
| SCHEMBL16246034 | 0.80 | MAPT (0.54) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL13735094 | 0.80 | MAPT (0.50) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL4752320 | 0.80 | HTR6 (0.55) | MAPTGAAGFERITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682663-A1 | 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-22 | — | — | EP | disclosed |