Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM1A | O60341 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CKS1B | P61024 | 4/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831286 | 0.82 | LMNA (0.75) | LMNAALDH1A1KDM1AKMT2ACKS1B | |
| SCHEMBL9832641 | 0.81 | PDE10A (0.61) | LMNAALDH1A1KDM1AKMT2ACKS1B | |
| SCHEMBL9205539 | 0.81 | ALDH1A1 (0.64) | LMNAALDH1A1KDM1AKMT2ACKS1B | |
| SCHEMBL9831482 | 0.80 | LMNA (0.59) | LMNAALDH1A1KDM1AKMT2ACKS1B | |
| SCHEMBL9830427 | 0.78 | ALDH1A1 (0.67) | LMNAALDH1A1KDM1AKMT2ACKS1B | |
| SCHEMBL7850997 | 0.75 | PDE10A (0.65) | ALDH1A1PDE10A | |
| SCHEMBL9831621 | 0.75 | NPC1 (0.59) | LMNAALDH1A1KDM1AKMT2ACKS1B | |
| SCHEMBL9833924 | 0.74 | CKS1B (0.84) | LMNAALDH1A1KDM1ACKS1BSKP2 | |
| SCHEMBL9220047 | 0.73 | NPC1 (0.54) | LMNAALDH1A1KDM1AKMT2ACKS1B | |
| SCHEMBL9831745 | 0.73 | ALDH1A1 (0.63) | LMNAALDH1A1KDM1ACKS1BSKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378508-B1 | Antidotes to modify the resistance of cultivated plants to agrochemical agents | CIBA GEIGY AG (CH) | 1995-03-01 | — | — | EP | disclosed |
| EP-0434624-B1 | Triazolylsulfonamides | CIBA GEIGY AG (CH) | 1995-02-08 | — | — | EP | disclosed |
| US-5217521-A | Preemergence, postemergence herbicides | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5175289-A | Antidotes for protecting cultivated plants from the phytotoxic action of herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-5041157-A | Protecting soybeans or cereals | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0434624-A1 | Triazolylsulfonamides | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |
| EP-0378508-A2 | Antidotes to modify the resistance of cultivated plants to agrochemical agents | CIBA-GEIGY AG (CH) | 1990-07-18 | — | — | EP | disclosed |