Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9214816 | 0.94 | MEN1 (0.53) | MEN1KMT2ASIGMAR1HRH3 | |
| SCHEMBL9216672 | 0.91 | CHRNB2 (0.47) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9207276 | 0.90 | ABCB1 (0.47) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9207682 | 0.88 | CHRNB2 (0.45) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9212297 | 0.86 | CHRNB4 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4ABCB1 | |
| SCHEMBL9211577 | 0.86 | BCHE (0.46) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL9210506 | 0.85 | CHRNB4 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9212603 | 0.85 | GAA (0.50) | MEN1KMT2AHRH3ABCB1 | |
| Hydrochloric Acid SCHEMBL9214061 | 0.85 | MEN1 (0.46) | MEN1KMT2AABCB1 | |
| Hydrochloric Acid SCHEMBL9210830 | 0.82 | CHRNB2 (0.46) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |