Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208638 | 1.00 | APEX1 (0.59) | APEX1BLMLMNATP53NPC1L1 | |
| SCHEMBL9628959 | 0.82 | APEX1 (0.69) | APEX1BLMLMNATP53SMN1; SMN2 | |
| SCHEMBL11522248 | 0.81 | APEX1 (0.58) | APEX1BLMLMNATP53SMN1; SMN2 | |
| SCHEMBL11107187 | 0.80 | APEX1 (0.54) | APEX1BLMLMNATP53 | |
| SCHEMBL10582437 | 0.80 | APEX1 (0.57) | APEX1BLMLMNATP53SMN1; SMN2 | |
| SCHEMBL11107180 | 0.79 | APEX1 (0.65) | APEX1BLMLMNATP53TSHR | |
| SCHEMBL9851227 | 0.78 | APEX1 (0.48) | APEX1BLMLMNATP53POLB | |
| SCHEMBL353782 | 0.78 | APEX1 (0.62) | APEX1BLMLMNATP53SMN1; SMN2 | |
| Oxiracetam SCHEMBL2596758 | 0.75 | APEX1 (1.00) | APEX1BLMTP53POLBCYP2C19 | |
| Oxiracetam SCHEMBL15789330 | 0.75 | APEX1 (1.00) | APEX1BLMTP53POLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3048657-A | — | — | None | — | — | JP | disclosed |
| EP-0408524-B1 | (Pyrrolidin-2-on-l-yl) acetamides as enhancers of learning and memory and pharmaceutical compositions comprising same | SIGMA TAU IND FARMACEUTI (IT) | 1995-11-08 | — | — | EP | disclosed |
| US-5061725-A | COGNITION ACTIVATORS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1991-10-29 | — | — | US | disclosed |
| JP-H0348657-A | (PYRROLIDIN-2-ON-1-YL)ACETAMIDE FOR ENHANCEMENT OF LEARNING AND MEMORY AND COMPOSITION CONTAINING THE SAME | SIGMA TAU IND FARMACEUT RIUNITE SPA | 1991-03-01 | — | — | JP | disclosed |
| EP-0408524-A1 | (Pyrrolidin-2-on-l-yl) acetamides as enhancers of learning and memory and pharmaceutical compositions comprising same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1991-01-16 | — | — | EP | disclosed |