Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 8/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213476 | 0.74 | PDK1 (0.36) | PDK1ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL9208015 | 0.69 | PDK1 (0.63) | PDK1ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL9212260 | 0.68 | PDK1 (0.47) | PDK1ALDH1A1POLBNPC1CYP2D6 | |
| SCHEMBL13768314 | 0.68 | PDK1 (0.61) | PDK1ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL9211341 | 0.67 | PDK1 (0.59) | PDK1ALDH1A1POLBKDM4EGAA | |
| SCHEMBL9216855 | 0.67 | PDK1 (0.55) | PDK1ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL3076050 | 0.66 | PDK1 (0.73) | PDK1ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL1002931 | 0.66 | PDK1 (0.73) | PDK1ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL9212949 | 0.66 | PDK1 (0.58) | PDK1ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL9214665 | 0.66 | MAPT (0.63) | PDK1ALDH1A1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0405976-A1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-02 | — | — | EP | disclosed |