Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28706461 | 0.95 | SMN1; SMN2 (0.90) | SMN1; SMN2GAAHPGDALDH1A1GLA | |
| SCHEMBL10823089 | 0.70 | GAA (0.53) | SMN1; SMN2GAAALDH1A1ALOX12L3MBTL1 | |
| SCHEMBL28318624 | 0.70 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAALDH1A1ALOX12L3MBTL1 | |
| SCHEMBL10823088 | 0.70 | GAA (0.53) | SMN1; SMN2GAAALDH1A1ALOX12L3MBTL1 | |
| SCHEMBL13321940 | 0.70 | GAA (0.53) | SMN1; SMN2GAAALDH1A1ALOX12L3MBTL1 | |
| SCHEMBL10787823 | 0.70 | GAA (0.53) | SMN1; SMN2GAAALDH1A1ALOX12L3MBTL1 | |
| SCHEMBL10426380 | 0.69 | SMN1; SMN2 (0.52) | SMN1; SMN2GAAALDH1A1ALOX12L3MBTL1 | |
| SCHEMBL778610 | 0.68 | SMN1; SMN2 (0.52) | SMN1; SMN2GAAHPGDALDH1A1ALOX12 | |
| SCHEMBL8618530 | 0.65 | ALDH1A1 (0.48) | SMN1; SMN2GAAHPGDALDH1A1NPC1 | |
| SCHEMBL11301792 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641337-A1 | CYCLIC ALKYLIDENE SUBSTITUTED PYRIDINE HERBICIDES | ROHM AND HAAS COMPANY (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1992021674-A1 | CYCLIC ALKYLIDENE SUBSTITUTED PYRIDINE HERBICIDES | MONSANTO COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5156670-A | Low soil mobility | MONSANTO COMPANY (US) | 1992-10-20 | — | — | US | disclosed |