Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217985 | 0.90 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9210632 | 0.89 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL9212533 | 0.84 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL9209076 | 0.78 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL9219252 | 0.76 | ALOX5 (0.75) | ALOX5 | |
| SCHEMBL9220221 | 0.75 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9211918 | 0.74 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL9209772 | 0.73 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL9218460 | 0.73 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL9219762 | 0.73 | ALOX5 (0.54) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385662-B1 | Heterocycles with inhibitory activity of 5-lipoxygenase | ZENECA LTD (GB) | 1995-12-13 | — | — | EP | claimed |