Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209076 | 0.89 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL9218182 | 0.87 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9210632 | 0.87 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL9219627 | 0.86 | ALOX5 (0.69) | ALOX5 | |
| SCHEMBL9212332 | 0.85 | ALOX5 (0.70) | ALOX5 | |
| SCHEMBL9216082 | 0.82 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL9219105 | 0.82 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9216262 | 0.81 | ALOX5 (0.78) | ALOX5 | |
| SCHEMBL9217278 | 0.80 | ALOX5 (0.49) | ALOX5 | |
| SCHEMBL9219457 | 0.79 | ALOX5 (0.62) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385662-B1 | Heterocycles with inhibitory activity of 5-lipoxygenase | ZENECA LTD (GB) | 1995-12-13 | — | — | EP | claimed |