Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 15/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314690 | 0.94 | PPARG (0.38) | PPARGPPARAS1PR1S1PR3MAOB | |
| SCHEMBL9218845 | 0.93 | PPARG (0.43) | PPARGPPARAS1PR1S1PR3MEN1 | |
| SCHEMBL9212152 | 0.88 | PPARG (0.34) | PPARGPPARAS1PR1S1PR3MEN1 | |
| SCHEMBL26714174 | 0.85 | PPARG (0.44) | PPARGPPARAS1PR1S1PR3MEN1 | |
| SCHEMBL9219323 | 0.81 | PPARG (0.36) | PPARGPPARAS1PR1S1PR3MEN1 | |
| SCHEMBL23972131 | 0.80 | HIF1A (0.46) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL676794 | 0.80 | HIF1A (0.46) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL19342159 | 0.80 | HIF1A (0.46) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL6032705 | 0.80 | HIF1A (0.46) | PPARGPPARAMEN1KMT2A | |
| SCHEMBL10014844 | 0.80 | HIF1A (0.46) | PPARGPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |
| EP-0433233-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-06-19 | — | — | EP | claimed |
| JP-4001191-A | — | — | None | — | — | JP | disclosed |
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | disclosed |
| US-5376677-A | Fungicides | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| JP-H041191-A | BENZO(B)THIOPHENE DERIVATIVE AND BACTERICIDE COMPOSITION | DR R MAAG AG | 1992-01-06 | — | — | JP | disclosed |
| EP-0433233-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-06-19 | — | — | EP | disclosed |