Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676794 | 1.00 | HIF1A (0.46) | HIF1AKMT2AMEN1TP53PPARG | |
| SCHEMBL23972131 | 1.00 | HIF1A (0.46) | HIF1AKMT2AMEN1TP53PPARG | |
| SCHEMBL10014844 | 1.00 | HIF1A (0.46) | HIF1AKMT2AMEN1TP53PPARG | |
| SCHEMBL6032705 | 1.00 | HIF1A (0.46) | HIF1AKMT2AMEN1TP53PPARG | |
| SCHEMBL8230371 | 0.88 | NPSR1 (0.41) | HIF1AKMT2AMEN1PPARGPPARA | |
| SCHEMBL23969503 | 0.87 | KMT2A (0.42) | HIF1AKMT2AMEN1PPARGPPARA | |
| SCHEMBL25552199 | 0.86 | HIF1A (0.48) | HIF1APPARGPPARA | |
| Picoxystrobin SCHEMBL7203031 | 0.86 | HIF1A (0.51) | HIF1AKMT2AMEN1PPARGPPARA | |
| SCHEMBL9892568 | 0.85 | HIF1A (0.48) | HIF1AKMT2AMEN1TP53PPARG | |
| SCHEMBL12635931 | 0.85 | HIF1A (0.64) | HIF1AKMT2AMEN1TP53PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10412966-B2 | Active substance combinations that have nematicidal, insecticidal, and fungicidal properties and are based on trifluorobutenyl compounds | ADAMA MAKHTESHIM LTD. (IL) | 2019-09-17 | — | — | US | disclosed |
| US-20170258088-A1 | ACTIVE SUBSTANCE COMBINATIONS THAT HAVE NEMATICIDAL, INSECTICIDAL, AND FUNGICIDAL PROPERTIES AND ARE BASED ON TRIFLUOROBUTENYL COMPOUNDS | ADAMA MAKHTESHIM LTD. (IL) | 2017-09-14 | — | — | US | disclosed |
| US-20170258088-A1 | ACTIVE SUBSTANCE COMBINATIONS THAT HAVE NEMATICIDAL, INSECTICIDAL, AND FUNGICIDAL PROPERTIES AND ARE BASED ON TRIFLUOROBUTENYL COMPOUNDS | ADAMA MAKHTESHIM LTD. (IL) | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10412966-B2 | Active substance combinations that have nematicidal, insecticidal, and fungicidal properties and are based on trifluorobutenyl compounds | DDT, ACHE, AADAC | HIF1A 4881/4885KMT2A 2967/4885MEN1 3318/4885 |
| US-20170258088-A1 | ACTIVE SUBSTANCE COMBINATIONS THAT HAVE NEMATICIDAL, INSECTICIDAL, AND FUNGICIDAL PROPERTIES AND ARE BASED ON TRIFLUOROBUTENYL COMPOUNDS | DDT, ACHE, AADAC | HIF1A 4881/4885KMT2A 2967/4885MEN1 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.