SCHEMBL9209102

SCHEMBL9209102

CC(C(=O)O)C1=CC=CCC1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 14/20 0.32
PTGS1 P23219 15/20 0.32
OPRK1 P41145 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
EPHX2 P34913 1/20 0.31
LMNA P02545 2/20 0.31
CYP2C9 P11712 2/20 0.31
AKR1C3 P42330 2/20 0.31
CXCR1 P25024 2/20 0.31
CXCR2 P25025 2/20 0.31
ALB P02768 1/20 0.31
ESR1 P03372 1/20 0.31
ALOX5 P09917 1/20 0.31
RARB P10826 1/20 0.31
ADRB3 P13945 1/20 0.31
NFKB1 P19838 1/20 0.31
HTR2A P28223 1/20 0.31
NR1I3 Q14994 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11580687 0.89 PTGS1 (0.35) PTGS2PTGS1OPRK1HTTKMT2A
SCHEMBL16234587 0.89
SCHEMBL11580295 0.86 PTGS1 (0.35) PTGS2PTGS1OPRK1HTTKMT2A
SCHEMBL11594962 0.82 PTGS2 (0.35) PTGS2PTGS1EPHX2LMNACYP2C9
SCHEMBL9392108 0.78 TSHR (0.34) KMT2ALMNATSHR
SCHEMBL11033490 0.77 GRM1 (0.32) KMT2ALMNACYP2C9
SCHEMBL13569736 0.75
SCHEMBL1054460 0.74
SCHEMBL12464250 0.74
Hydrochloric Acid SCHEMBL9826804 0.74 GRM1 (0.30) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0357557-A2 Synergistic mixture CIBA-GEIGY AG (CH) 1990-03-07 EP claimed
EP-0378508-B1 Antidotes to modify the resistance of cultivated plants to agrochemical agents CIBA GEIGY AG (CH) 1995-03-01 EP disclosed
EP-0378508-A2 Antidotes to modify the resistance of cultivated plants to agrochemical agents CIBA-GEIGY AG (CH) 1990-07-18 EP disclosed
EP-0357557-A2 Synergistic mixture CIBA-GEIGY AG (CH) 1990-03-07 EP disclosed
US-4098881-A COMPOSITIONS TO CONTROL THE CHRONIC EFFECTS OF EXPOSURE TO SUNLIGHT COMPRISING CONJUGATED DIENES THE PROCTER & GAMBLE COMPANY (US) 1978-07-04 US disclosed