SCHEMBL11033490

SCHEMBL11033490

NC(C(=O)O)C1=CC=CCC1

nearest known ligand 0.32

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 4/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31
LMNA P02545 1/20 0.31
GRM5 P41594 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GRM8 O00222 1/20 0.31
GRM6 O15303 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
DRD3 P35462 1/20 0.31
GRM4 Q14833 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9826804 0.96 GRM1 (0.30) GRM1MEN1KMT2ATDP1CYP1A2
Hydrochloric Acid SCHEMBL9826797 0.81
SCHEMBL16316539 0.79
SCHEMBL28166938 0.77
SCHEMBL9209102 0.77 PTGS2 (0.32) KMT2ACYP2C9LMNA
SCHEMBL19074490 0.76 POLB (0.41) MEN1KMT2AHSD17B10LMNA
SCHEMBL3671823 0.74
SCHEMBL14198716 0.74 CYP2D6 (0.34) MEN1KMT2ACYP1A2CYP2D6CYP2C9
SCHEMBL7902081 0.71
SCHEMBL13672987 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0038641-A1 Process for producing D-2-amino-2-(1,4-cyclohexadienyl) acetic acid NIPPON KASEI CHEMICAL CO., LTD. (JP) 1981-10-28 EP claimed
US-4043991-A Preparation of peptides and cephalosporins SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-23 US claimed
JP-59076087-A None JP disclosed
JP-S5976087-A PREPARATION OF CEPHALOSPORIN DERIVATIVE TOKAWA TETSUO 1984-04-28 JP disclosed
US-4043991-A Preparation of peptides and cephalosporins SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-23 US disclosed