Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.61 |
| ▸ | BCR | P11274 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25485549 | 0.96 | ACHE (0.65) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL20111194 | 0.95 | MAPK1 (0.59) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL3743494 | 0.90 | ABL1 (0.71) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL920933 | 0.90 | ABL1 (0.71) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL20022095 | 0.86 | ABL1 (0.72) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL17922686 | 0.86 | NPC1 (0.50) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL20022136 | 0.83 | ABL1 (0.69) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL20022108 | 0.83 | ABL1 (0.69) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL12714843 | 0.82 | ACHE (0.83) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL3676881 | 0.82 | ACHE (0.83) | ABL1ABCB1BCRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836706-B2 | Bacterial efflux pump inhibitors | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190055188-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2019-02-21 | — | — | US | disclosed |
| WO-2017147335-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836706-B2 | Bacterial efflux pump inhibitors | ABCB11, ABCB1, SLC47A1 | ABL1 1889/4885ABCB1 2/4885BCR 1002/4885 |
| US-20190055188-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, SLC47A1 | ABL1 1889/4885ABCB1 2/4885BCR 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.