Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 14/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421485 | 0.77 | SOD1 (0.51) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9201354 | 0.75 | SOD1 (0.47) | ALDH1A1CYP2C19KDM4ELMNAMAPT | |
| SCHEMBL9209228 | 0.75 | CYP1A2 (0.51) | CA12CA4CA7CA9CA14 | |
| SCHEMBL9208673 | 0.74 | SOD1 (0.56) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL8421424 | 0.74 | SOD1 (0.56) | CYP3A4CYP2D6ALDH1A1KDM4ELMNA | |
| SCHEMBL8423745 | 0.73 | SOD1 (0.47) | CYP1A2MEN1KMT2AKDM4EADORA2A | |
| SCHEMBL9204316 | 0.73 | TOP2A (0.52) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8421903 | 0.73 | SOD1 (0.55) | CYP3A4CYP2D6ALDH1A1KDM4ELMNA | |
| SCHEMBL11882576 | 0.72 | CA12 (1.00) | CA12CA4CA7CA9CA14 | |
| SCHEMBL9202631 | 0.72 | TOP2A (0.45) | CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497809-B1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-06-28 | — | — | EP | disclosed |
| US-5162320-A | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1992-11-10 | — | — | US | disclosed |
| EP-0497809-A1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES. | BOEHRINGER MANNHEIM ITALIA (IT) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991006540-A1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1991-05-16 | — | — | WO | disclosed |