SCHEMBL9209495

SCHEMBL9209495

CCCN(c1ccncc1)N1CC(C)c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 13/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13663906 0.81 BCHE (0.37) SLC6A2
SCHEMBL9198842 0.75 SLC6A2 (0.51) SLC6A2
Oxalic Acid SCHEMBL9200669 0.69 SLC6A2 (0.48) SLC6A2
SCHEMBL9501335 0.68 CACNA1I (0.54)
SCHEMBL8860238 0.68 SLC6A2 (0.49) SLC6A2
SCHEMBL7609760 0.67 SLC6A2 (0.59) SLC6A2
SCHEMBL9663535 0.67 SLC6A2 (1.00) SLC6A2
SCHEMBL6673643 0.66 SLC6A2 (0.54) SLC6A2
Hydrochloric Acid SCHEMBL7616450 0.66 SLC6A2 (0.58) SLC6A2
SCHEMBL9381608 0.66 SLC6A2 (0.47) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415103-B1 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments HOECHST ROUSSEL PHARMA (US) 1995-02-01 EP disclosed
US-5296488-A Method of using 2,3-dihydro-1-(pyridinylamino)-indoles as anticonvulsants and for the enhancement of memory HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1994-03-22 US disclosed
EP-0415103-A1 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-03-06 EP disclosed