Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | NAMPT | P43490 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219229 | 0.91 | NPSR1 (0.43) | NPSR1GAANAMPTCA12CA1 | |
| SCHEMBL9215077 | 0.86 | NPSR1 (0.41) | NPSR1GAANAMPTALDH1A1CA12 | |
| SCHEMBL9218048 | 0.85 | ABCC9 (0.39) | NPSR1GAANAMPTALDH1A1CA12 | |
| SCHEMBL9215473 | 0.85 | NPSR1 (0.38) | NPSR1GAANAMPTALDH1A1CA12 | |
| SCHEMBL9217581 | 0.83 | NPSR1 (0.36) | NPSR1GAANAMPTCA12CA1 | |
| SCHEMBL9217189 | 0.83 | ABCC9 (0.34) | NPSR1GAAALDH1A1CA12CA1 | |
| SCHEMBL9218931 | 0.83 | NPSR1 (0.37) | NPSR1GAARXFP1NAMPTALDH1A1 | |
| SCHEMBL9218026 | 0.82 | NPSR1 (0.39) | NPSR1GAANAMPTCA12CA1 | |
| SCHEMBL9215385 | 0.82 | NPSR1 (0.37) | NPSR1GAANAMPTCA12CA1 | |
| SCHEMBL9217130 | 0.82 | NPSR1 (0.37) | NPSR1GAANAMPTALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |