Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217235 | 0.95 | NPSR1 (0.35) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| SCHEMBL9222097 | 0.94 | NPSR1 (0.34) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| SCHEMBL9218094 | 0.91 | MAPT (0.35) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| SCHEMBL9221306 | 0.88 | IDH1 (0.34) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| SCHEMBL9220132 | 0.88 | CA12 (0.35) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| SCHEMBL9211589 | 0.86 | MAPT (0.37) | MAPTALDH1A1LMNATP53HTT | |
| SCHEMBL9219229 | 0.84 | NPSR1 (0.43) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| SCHEMBL9219603 | 0.83 | ACLY (0.33) | TDP1GAAACLY | |
| SCHEMBL9209710 | 0.83 | NPSR1 (0.39) | ABCC9ABCC8KCNJ11KCNJ8MAPT | |
| SCHEMBL9217252 | 0.80 | HTT (0.35) | MAPTALDH1A1LMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |