Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209739 | 0.88 | NR1I2 (0.54) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL10413141 | 0.87 | PLAU (0.51) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705941 | 0.86 | MEN1 (0.44) | MEN1KMT2AESR1LMNABRD4 | |
| SCHEMBL9705669 | 0.85 | CYP2D6 (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9200429 | 0.82 | PLAU (0.49) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9436198 | 0.81 | LMNA (0.42) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL10414529 | 0.81 | NR1I2 (0.42) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8875258 | 0.79 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8875264 | 0.79 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9705738 | 0.78 | KDM4E (0.41) | NR1I2CYP3A4CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945164-A | 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof | STERLING DRUG INC. (US) | 1990-07-31 | — | — | US | disclosed |