Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28303246 | 0.84 | HTT (0.47) | MEN1KMT2APOLB | |
| SCHEMBL27821681 | 0.78 | HDAC6 (0.49) | MEN1KMT2AAPAF1POLBCTDSP1 | |
| SCHEMBL28010037 | 0.78 | HDAC6 (0.49) | MEN1KMT2AAPAF1POLBCTDSP1 | |
| SCHEMBL28493115 | 0.77 | KMT2A (0.47) | MEN1KMT2AAPAF1CASRTSHR | |
| SCHEMBL28493114 | 0.77 | KMT2A (0.47) | MEN1KMT2AAPAF1CASRTSHR | |
| SCHEMBL10638831 | 0.77 | OPRM1 (0.53) | MEN1KMT2APKMLTB4RLTB4R2 | |
| SCHEMBL7511468 | 0.76 | HDAC3 (0.49) | MEN1KMT2AAPAF1PKMHSD17B10 | |
| SCHEMBL27882319 | 0.76 | HDAC6 (0.47) | MEN1KMT2AAPAF1POLBCTDSP1 | |
| SCHEMBL7398854 | 0.75 | POLB (0.51) | MEN1KMT2AAPAF1POLBMAPT | |
| SCHEMBL10154589 | 0.75 | CASR (0.69) | MEN1KMT2ACASRGPR139POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |