SCHEMBL921222

SCHEMBL921222

Cc1cc(C(C)c2ccc(C)c(O)c2)ccc1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.64
PTGS1 P23219 1/20 0.64
CACNA1C Q13936 1/20 0.64
TDP1 Q9NUW8 5/20 0.45
TP53 P04637 1/20 0.45
TSHR P16473 2/20 0.42
CASP1 P29466 1/20 0.42
PDE10A Q9Y233 1/20 0.42
KDM4E B2RXH2 5/20 0.41
MAPT P10636 4/20 0.41
ESR1 P03372 4/20 0.41
ESR2 Q92731 3/20 0.41
HIF1A Q16665 3/20 0.41
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 2/20 0.41
ALOX12 P18054 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29657745 0.92 TDP1 (0.52) TRPA1PTGS1CACNA1CTDP1TP53
SCHEMBL921090 0.92 TDP1 (0.52) TRPA1PTGS1CACNA1CTDP1TP53
SCHEMBL29948126 0.92 TDP1 (0.52) TRPA1PTGS1CACNA1CTDP1TP53
SCHEMBL921036 0.92 TRPA1 (0.75) TRPA1PTGS1CACNA1CTDP1TSHR
SCHEMBL16351136 0.90 TRPA1 (0.50) TRPA1PTGS1CACNA1CTDP1TP53
SCHEMBL2484676 0.84 ESR1 (0.64) TRPA1PTGS1CACNA1CTDP1TP53
SCHEMBL17716504 0.84 TDP1 (0.45) TRPA1PTGS1CACNA1CTDP1TP53
SCHEMBL20217117 0.82 ESR1 (0.45) TRPA1PTGS1CACNA1CTDP1TP53
SCHEMBL7053020 0.82 TYR (0.49) TRPA1PTGS1CACNA1CTDP1TP53
SCHEMBL24411263 0.80 PTGS1 (0.43) TRPA1PTGS1CACNA1CTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101334592-B Electrophotographic photoreceptor MITSUBISHI CHEM CORP 2013-11-06 CN disclosed
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
CN-1985218-B Electrophotographic photoreceptor MITSUBISHI CHEM CORP 2012-09-05 CN disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
EP-1770447-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY MITSUBISHI CHEM CORP (JP) 2011-03-16 EP disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-20100183332-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-07-22 US disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
CN-101334592-A Electrophotographic photoreceptor MITSUBISHI CHEM CORP (JP) 2008-12-31 CN disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
CN-1985218-A Electrophotographic photoreceptor MITSUBISHI CHEM CORP (JP) 2007-06-20 CN disclosed