Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040517 | 0.96 | MAPT (0.39) | MAPTALDH1A1L3MBTL1KDM4ECASP6 | |
| SCHEMBL9080330 | 0.96 | MAPT (0.39) | MAPTALDH1A1L3MBTL1KDM4ECASP6 | |
| SCHEMBL9218810 | 0.91 | FTO (0.48) | MAPTALDH1A1L3MBTL1KDM4ECASP6 | |
| SCHEMBL9079682 | 0.88 | FTO (0.45) | MAPTALDH1A1L3MBTL1KDM4ECASP6 | |
| SCHEMBL9115379 | 0.85 | FTO (0.36) | MAPTL3MBTL1KDM4ECASP6KMT2A | |
| SCHEMBL9113483 | 0.84 | FTO (0.47) | MAPTL3MBTL1KDM4ECASP6KMT2A | |
| SCHEMBL9211382 | 0.83 | FTO (0.48) | MAPTL3MBTL1KDM4ECASP6KMT2A | |
| SCHEMBL9220267 | 0.82 | FTO (0.52) | MAPTALDH1A1L3MBTL1KDM4ECASP6 | |
| SCHEMBL9048246 | 0.81 | FTO (0.33) | MAPTKDM4ECASP6KMT2ALMNA | |
| SCHEMBL9038069 | 0.81 | FTO (0.44) | MAPTL3MBTL1KDM4ECASP6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000490-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-05 | — | — | WO | claimed |
| WO-1995000490-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-01-05 | — | — | WO | disclosed |