Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.72 |
| ▸ | DRD2 | P14416 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
| ▸ | HTR7 | P34969 | 1/20 | 0.72 |
| ▸ | HTR6 | P50406 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9394365 | 0.99 | HTR1A (0.70) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9209001 | 0.88 | HTR1A (0.70) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9205690 | 0.87 | HTR1A (0.72) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9375707 | 0.87 | — | — | |
| SCHEMBL9210256 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL9380255 | 0.86 | — | — | |
| SCHEMBL9383206 | 0.84 | HTR1A (0.98) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9035939 | 0.84 | HTR1A (0.80) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9594968 | 0.84 | HTR1A (0.82) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9209048 | 0.84 | HTR1A (0.69) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117731-A | Heteroaromatic compounds with antipsychotic activity | WELLCOME FOUND (GB) | 1996-02-28 | — | — | CN | claimed |
| EP-0683778-A1 | HETEROAROMATIC COMPOUNDS WITH ANTIPSYCHOTIC ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-11-29 | — | — | EP | claimed |
| WO-1994018196-A1 | HETEROAROMATIC COMPOUNDS WITH ANTIPSYCHOTIC ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-08-18 | — | — | WO | claimed |
| CN-1117731-A | Heteroaromatic compounds with antipsychotic activity | WELLCOME FOUND (GB) | 1996-02-28 | — | — | CN | disclosed |
| EP-0683778-A1 | HETEROAROMATIC COMPOUNDS WITH ANTIPSYCHOTIC ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994018196-A1 | HETEROAROMATIC COMPOUNDS WITH ANTIPSYCHOTIC ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-08-18 | — | — | WO | disclosed |