Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21890305 | 0.98 | DNM1 (0.50) | DNM1EPHX1OPRM1ALDH1A1TSHR | |
| SCHEMBL16649021 | 0.97 | DNM1 (0.42) | DNM1EPHX1OPRM1ALDH1A1TSHR | |
| SCHEMBL18898174 | 0.95 | DNM1 (0.46) | DNM1EPHX1OPRM1ALDH1A1TSHR | |
| SCHEMBL2334045 | 0.95 | DNM1 (0.46) | DNM1EPHX1OPRM1ALDH1A1TSHR | |
| SCHEMBL19890567 | 0.95 | DNM1 (0.46) | DNM1EPHX1OPRM1ALDH1A1TSHR | |
| SCHEMBL5371278 | 0.95 | DNM1 (0.43) | DNM1EPHX1ALDH1A1TSHRLMNA | |
| SCHEMBL28177815 | 0.91 | DNM1 (0.42) | DNM1EPHX1OPRM1ALDH1A1TSHR | |
| SCHEMBL8533031 | 0.91 | DNM1 (0.42) | DNM1EPHX1OPRM1ALDH1A1TSHR | |
| SCHEMBL20798577 | 0.90 | DNM1 (0.40) | DNM1EPHX1OPRM1ALDH1A1TSHR | |
| SCHEMBL26220887 | 0.90 | DNM1 (0.40) | DNM1EPHX1ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |