SCHEMBL2334045

SCHEMBL2334045

CCCCCCCCCCC(CCCCCCCCCC)NCCC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.46
EPHX1 P07099 2/20 0.46
LMNA P02545 1/20 0.41
TSHR P16473 2/20 0.40
THRB P10828 1/20 0.40
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH4 P08319 1/20 0.39
ADH7 P40394 1/20 0.39
OPRM1 P35372 1/20 0.39
SIGMAR1 Q99720 3/20 0.38
ALDH1A1 P00352 1/20 0.38
GPR84 Q9NQS5 2/20 0.37
FDPS P14324 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18898174 1.00 DNM1 (0.46) DNM1EPHX1LMNATSHRTHRB
SCHEMBL19890567 1.00 DNM1 (0.46) DNM1EPHX1LMNATSHRTHRB
SCHEMBL21890305 0.98 DNM1 (0.50) DNM1EPHX1LMNATSHRTHRB
SCHEMBL16649021 0.97 DNM1 (0.42) DNM1EPHX1LMNATSHRTHRB
SCHEMBL8533031 0.95 DNM1 (0.42) DNM1EPHX1LMNATSHRTHRB
SCHEMBL28177815 0.95 DNM1 (0.42) DNM1EPHX1LMNATSHRTHRB
SCHEMBL9210833 0.95 DNM1 (0.46) DNM1EPHX1LMNATSHRADH1B
SCHEMBL20299289 0.91 DNM1 (0.42) DNM1EPHX1LMNATSHRTHRB
SCHEMBL5014624 0.91 DNM1 (0.42) DNM1EPHX1LMNATSHRTHRB
SCHEMBL117274 0.91 DNM1 (0.42) DNM1EPHX1LMNATSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003369-B2 Bacteriolytic agent SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2011-08-23 US disclosed
US-7582694-B2 Antimicrobial lubricant for wood fiber-plastic composites LONZA, INC. (US) 2009-09-01 US disclosed
US-20090143569-A1 BACTERIOLYTIC AGENT SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2009-06-04 US disclosed
EP-1567586-B1 ANTIMICROBIAL LUBRICANT FOR WOOD FIBER-PLASTIC COMPOSITES LONZA AG (US) 2008-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090143569-A1 BACTERIOLYTIC AGENT PRKCH, PRKCA, PRKCI DNM1 1223/4885EPHX1 4663/4885LMNA 1735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.