SCHEMBL921090

SCHEMBL921090

Cc1cc(C(C)c2ccc(O)c(C)c2)ccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.52
TP53 P04637 1/20 0.52
TRPA1 O75762 1/20 0.50
PTGS1 P23219 1/20 0.50
CACNA1C Q13936 1/20 0.50
PDE10A Q9Y233 1/20 0.48
ESR1 P03372 7/20 0.48
ESR2 Q92731 5/20 0.48
PDCD1 Q15116 1/20 0.48
CD274 Q9NZQ7 1/20 0.48
HIF1A Q16665 3/20 0.43
AR P10275 3/20 0.43
ALDH1A1 P00352 2/20 0.43
ALOX12 P18054 2/20 0.43
GAA P10253 1/20 0.43
HTT P42858 1/20 0.43
KDM4E B2RXH2 4/20 0.42
MAPT P10636 4/20 0.42
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29657745 1.00 TDP1 (0.52) TDP1TP53TRPA1PTGS1CACNA1C
SCHEMBL29948126 1.00 TDP1 (0.52) TDP1TP53TRPA1PTGS1CACNA1C
SCHEMBL16351136 0.94 TRPA1 (0.50) TDP1TP53TRPA1PTGS1CACNA1C
SCHEMBL921222 0.92 TRPA1 (0.64) TDP1TP53TRPA1PTGS1CACNA1C
SCHEMBL2484676 0.92 ESR1 (0.64) TDP1TP53TRPA1PTGS1CACNA1C
SCHEMBL17716504 0.92 TDP1 (0.45) TDP1TP53TRPA1PTGS1CACNA1C
SCHEMBL7053020 0.90 TYR (0.49) TDP1TP53TRPA1PTGS1CACNA1C
SCHEMBL20217117 0.90 ESR1 (0.45) TDP1TP53TRPA1PTGS1CACNA1C
SCHEMBL1397101 0.86 PTGS1 (0.68) TDP1TP53TRPA1PTGS1CACNA1C
SCHEMBL28878142 0.86 TDP1 (0.52) TDP1TP53TRPA1PTGS1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 841 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2447299-B1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO (JP) 2017-11-29 EP claimed
US-8519082-B2 Polycarbonate copolymer, coating liquid using same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-08-27 US claimed
EP-2447299-A1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Idemitsu Kosan Co., Ltd. (JP) 2012-05-02 EP claimed
US-20120100474-A1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2012-04-26 US claimed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US claimed
EP-1770447-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY MITSUBISHI CHEM CORP (JP) 2011-03-16 EP claimed
US-7718337-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2010-05-18 US claimed
US-7671167-B2 Poly(arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-02 US claimed
US-20090247724-A1 POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-10-01 US claimed
US-20090081570-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-26 US claimed
EP-1969030-A2 POLY (ARYLENE ETHER) COPOLYMER GENERAL ELECTRIC COMPANY (US) 2008-09-17 EP claimed
EP-1966279-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD General Electric Company (US) 2008-09-10 EP claimed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US claimed
WO-2007067669-A2 POLY (ARYLENE ETHER) COPOLYMER GENERAL ELECTRIC COMPANY (US) 2007-06-14 WO claimed
US-20070135609-A1 Poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-06-14 US claimed
WO-2007058779-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD GENERAL ELECTRIC COMPANY (US) 2007-05-24 WO claimed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US claimed
EP-1770447-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Mitsubishi Chemical Corporation (JP) 2007-04-04 EP claimed
US-4775739-A IMPROVED FLOWABILITY MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1988-10-04 US claimed
US-4609928-A LEUCO DYES, COLOR DEVELOPERS, BISHENOL, P-HYDROXYBENZOIC ACID ESTER, POROSITY, FILLERS RICOH COMPANY, LTD. (JP) 1986-09-02 US claimed