Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32675970 | 0.85 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRCYP3A4LMNA | |
| SCHEMBL4653028 | 0.85 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRCYP3A4LMNA | |
| SCHEMBL19091741 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRCYP3A4LMNA | |
| SCHEMBL81340 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRCYP3A4LMNA | |
| SCHEMBL11810737 | 0.80 | — | — | |
| SCHEMBL31050879 | 0.78 | LMNA (0.48) | ALDH1A1TDP1TSHRCYP3A4LMNA | |
| SCHEMBL4655337 | 0.77 | — | — | |
| SCHEMBL25907082 | 0.76 | LMNA (0.52) | ALDH1A1TDP1TSHRLMNADNM1 | |
| SCHEMBL28610108 | 0.76 | CYP3A4 (0.38) | ALDH1A1TDP1TSHRCYP3A4LMNA | |
| SCHEMBL17523814 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |