SCHEMBL9211319

SCHEMBL9211319

[O-][S+](CN1CCOCC1)c1nc2cnccc2s1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 2/20 0.40
LTA4H P09960 2/20 0.38
LATS1 O95835 2/20 0.37
LATS2 Q9NRM7 2/20 0.37
USP2 O75604 1/20 0.36
GAA P10253 1/20 0.36
TBK1 Q9UHD2 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
NFATC1 O95644 1/20 0.34
GSK3B P49841 1/20 0.34
DYRK1A Q13627 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9215779 0.76 PDK1 (0.38) LTA4HUSP2GAAALDH1A1KDM4E
SCHEMBL9639429 0.71 ADORA2A (0.34) RAB9ASMN1; SMN2NPC1
SCHEMBL9214919 0.71 USP2 (0.47) MYCUSP2GAAALDH1A1KDM4E
SCHEMBL24359019 0.71 SMN1; SMN2 (0.66) USP2GAAHRH3ALDH1A1PKM
SCHEMBL9209935 0.69 CYP2C9 (0.35) MYCLTA4HLATS1LATS2HRH3
SCHEMBL9211312 0.69 MKNK1 (0.33) MYCLATS1HRH3IRAK4
SCHEMBL9743920 0.69 TMEM97 (0.44) USP2GAA
SCHEMBL9216533 0.68 LATS1 (0.34) LTA4HLATS1LATS2HRH3
SCHEMBL5848920 0.68 CYP2A6 (0.31) LTA4HHRH3
SCHEMBL9208395 0.68 CHRNB2 (0.40) HRH3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0405976-B1 Azole derivatives and antiulcerative composition containing same MEIJI SEIKA CO (JP) 1995-04-05 EP disclosed
US-5200407-A Antisecretory agents MEIJI SEIKA KABURHIKI KAISHA (JP) 1993-04-06 US disclosed
US-5141946-A Antisecretory agents; acid resistance MEIJI SEIKA KABUSHIKI KAISHA (JP) 1992-08-25 US disclosed
US-5079255-A Nontoxic, acid stability MEIJI SEIKA KABUSHIKI KAISHA (JP) 1992-01-07 US disclosed
EP-0405976-A1 Azole derivatives and antiulcerative composition containing same MEIJI SEIKA KABUSHIKI KAISHA (JP) 1991-01-02 EP disclosed