Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210517 | 1.00 | DNM1 (0.39) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9213235 | 1.00 | DNM1 (0.39) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9210728 | 0.96 | DNM1 (0.39) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9876653 | 0.93 | DNM1 (0.35) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL16985042 | 0.89 | USP2 (0.42) | TSHRALDH1A1USP2LMNACYP1A2 | |
| SCHEMBL7077181 | 0.89 | USP2 (0.42) | TSHRALDH1A1USP2LMNACYP1A2 | |
| SCHEMBL20374717 | 0.89 | DNM1 (0.38) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL16985055 | 0.86 | ALDH1A1 (0.34) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL28859416 | 0.86 | TSHR (0.42) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL14109879 | 0.86 | TSHR (0.42) | DNM1TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |