Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210274 | 0.85 | NQO1 (0.67) | ACHENQO1MAOBKDM4EALDH1A1 | |
| SCHEMBL9208386 | 0.79 | NQO1 (0.56) | MEN1KMT2ANQO1KDM4EALDH1A1 | |
| SCHEMBL8806342 | 0.77 | NQO1 (0.63) | NQO1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7359563 | 0.77 | CYP2C9 (0.58) | ACHEMEN1KMT2ANQO1KDM4E | |
| SCHEMBL8808578 | 0.77 | NQO1 (0.67) | RAB9ANQO1MAOBMAPTTHRB | |
| SCHEMBL5617745 | 0.76 | ACHE (0.88) | ACHEMEN1KMT2ARAB9AMAOB | |
| SCHEMBL8806699 | 0.75 | NQO1 (0.52) | MEN1KMT2ANQO1KDM4EALDH1A1 | |
| SCHEMBL5072364 | 0.74 | NQO1 (0.71) | MEN1KMT2ANQO1KDM4EALDH1A1 | |
| SCHEMBL7432232 | 0.74 | ACHE (0.84) | ACHEMEN1KMT2ARAB9AMAOB | |
| SCHEMBL9210230 | 0.74 | VKORC1 (0.76) | MEN1KMT2ANQO1MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682663-A1 | 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-22 | — | — | EP | claimed |
| EP-0682663-A1 | 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-22 | — | — | EP | disclosed |