Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209170 | 0.97 | MEN1 (0.46) | MEN1KMT2AL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL6936582 | 0.97 | L3MBTL1 (0.49) | MEN1KMT2AL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL9212111 | 0.95 | MEN1 (0.44) | MEN1KMT2AL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL5500482 | 0.95 | MEN1 (0.44) | MEN1KMT2AL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL9213248 | 0.93 | KMT2A (0.40) | MEN1KMT2AL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL9218677 | 0.91 | L3MBTL1 (0.39) | MEN1KMT2AL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL9213879 | 0.90 | L3MBTL1 (0.39) | MEN1KMT2AL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL9215732 | 0.89 | EGFR (0.38) | MEN1KMT2AL3MBTL1PTPN1NPSR1 | |
| SCHEMBL9221161 | 0.88 | L3MBTL1 (0.38) | MEN1KMT2AL3MBTL1PTPN1NPSR1 | |
| SCHEMBL9222024 | 0.88 | ESR1 (0.39) | MEN1KMT2AL3MBTL1PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |