Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213879 | 0.98 | L3MBTL1 (0.39) | EGFRERBB2MAPTL3MBTL1TP53 | |
| SCHEMBL9218677 | 0.97 | L3MBTL1 (0.39) | EGFRERBB2MAPTL3MBTL1TP53 | |
| SCHEMBL9217824 | 0.95 | L3MBTL1 (0.37) | EGFRERBB2MAPTL3MBTL1TP53 | |
| SCHEMBL5500482 | 0.94 | MEN1 (0.44) | EGFRERBB2MAPTL3MBTL1TP53 | |
| SCHEMBL9218562 | 0.93 | MAPT (0.41) | MAPTL3MBTL1TP53THRBKMT2A | |
| SCHEMBL9219657 | 0.93 | L3MBTL1 (0.36) | EGFRERBB2MAPTL3MBTL1TP53 | |
| SCHEMBL9681518 | 0.93 | NPC1 (0.39) | MAPTL3MBTL1TP53THRBMEN1 | |
| SCHEMBL9209170 | 0.91 | MEN1 (0.46) | EGFRERBB2MAPTL3MBTL1MEN1 | |
| SCHEMBL9221161 | 0.91 | L3MBTL1 (0.38) | MAPTL3MBTL1TP53THRBMEN1 | |
| SCHEMBL9220046 | 0.90 | L3MBTL1 (0.36) | MAPTL3MBTL1TP53THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |