Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.54 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211412 | 1.00 | ABCC9 (0.61) | ABCC9KDM4EABCB1KCNE1KCNQ1 | |
| SCHEMBL9211421 | 1.00 | ABCC9 (0.61) | ABCC9KDM4EABCB1KCNE1KCNQ1 | |
| SCHEMBL9214331 | 0.88 | ABCC9 (0.56) | ABCC9KDM4EABCB1KCNE1KCNQ1 | |
| SCHEMBL9214323 | 0.88 | ABCC9 (0.56) | ABCC9KDM4EABCB1KCNE1KCNQ1 | |
| SCHEMBL9215236 | 0.87 | ABCB1 (0.56) | ABCC9KDM4EABCB1 | |
| SCHEMBL9212222 | 0.87 | ABCC9 (0.55) | ABCC9KDM4EABCB1 | |
| SCHEMBL9217991 | 0.87 | KDM4E (0.57) | ABCC9KDM4EABCB1KCNE1KCNQ1 | |
| SCHEMBL9215247 | 0.87 | ABCB1 (0.56) | ABCC9KDM4EABCB1 | |
| SCHEMBL9217975 | 0.87 | KDM4E (0.57) | ABCC9KDM4EABCB1KCNE1KCNQ1 | |
| SCHEMBL9212230 | 0.87 | ABCC9 (0.55) | ABCC9KDM4EABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375449-B1 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1995-02-15 | — | — | EP | claimed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | claimed |
| EP-0375449-B1 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1995-02-15 | — | — | EP | disclosed |
| EP-0375449-A2 | Benzopyran-type compounds | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |