SCHEMBL9215247

SCHEMBL9215247

CC(C)C(=O)NC1C(O)c2cc(C#N)ccc2OC1(C)C

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 12/20 0.56
ABCC9 O60706 7/20 0.55
KDM4E B2RXH2 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9215250 1.00 ABCB1 (0.56) ABCB1ABCC9KDM4E
SCHEMBL9215236 1.00 ABCB1 (0.56) ABCB1ABCC9KDM4E
SCHEMBL9211412 0.87 ABCC9 (0.61) ABCB1ABCC9KDM4E
SCHEMBL9211421 0.87 ABCC9 (0.61) ABCB1ABCC9KDM4E
SCHEMBL9211433 0.87 ABCC9 (0.61) ABCB1ABCC9KDM4E
SCHEMBL9213480 0.87 ABCB1 (0.54) ABCB1ABCC9KDM4E
SCHEMBL9213473 0.87 ABCB1 (0.54) ABCB1ABCC9KDM4E
SCHEMBL9214331 0.85 ABCC9 (0.56) ABCB1ABCC9KDM4E
SCHEMBL9214323 0.85 ABCC9 (0.56) ABCB1ABCC9KDM4E
SCHEMBL9217975 0.84 KDM4E (0.57) ABCB1ABCC9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0375449-B1 Benzopyran-type compounds BEECHAM GROUP PLC (GB) 1995-02-15 EP claimed
EP-0375449-A2 Benzopyran-type compounds BEECHAM GROUP PLC (GB) 1990-06-27 EP claimed
EP-0375449-B1 Benzopyran-type compounds BEECHAM GROUP PLC (GB) 1995-02-15 EP disclosed
EP-0375449-A2 Benzopyran-type compounds BEECHAM GROUP PLC (GB) 1990-06-27 EP disclosed