SCHEMBL921158

SCHEMBL921158

CCc1ccc(Oc2ccc(O)c(CC)c2)cc1O

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
BACE1 P56817 1/20 0.43
POLB P06746 1/20 0.42
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
HSP90AA1 P07900 2/20 0.41
HSP90AB1 P08238 1/20 0.41
HSD17B1 P14061 1/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
LTA4H P09960 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921473 0.92 ESR1 (0.52) ESR1ESR2BACE1THRATHRB
SCHEMBL921465 0.92 POLB (0.47) ESR1ESR2POLBHSP90AA1MEN1
SCHEMBL12806942 0.91 TRPA1 (0.45) ESR1ESR2POLBHSP90AA1LTA4H
SCHEMBL12806918 0.87 LTA4H (0.55) ESR1ESR2POLBMEN1KMT2A
SCHEMBL12806604 0.86 ESR1 (0.47) ESR1ESR2BACE1POLBMEN1
SCHEMBL12806625 0.85 HSP90AA1 (0.50) ESR1ESR2BACE1POLBHSP90AA1
SCHEMBL12806594 0.84 LTA4H (0.57) ESR1ESR2POLBHSP90AA1MEN1
SCHEMBL12806561 0.84 POLB (0.41) ESR1ESR2POLBMEN1MAPT
SCHEMBL12806640 0.84 LTA4H (0.53) POLBLTA4H
SCHEMBL12806934 0.82 HSP90AA1 (0.47) POLBHSP90AA1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
EP-1770447-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY MITSUBISHI CHEM CORP (JP) 2011-03-16 EP disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
EP-2154575-A2 Electrophotographic photoreceptor Mitsubishi Chemical Corporation (JP) 2010-02-17 EP disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
EP-1770447-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Mitsubishi Chemical Corporation (JP) 2007-04-04 EP disclosed