Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102393 | 0.74 | BRD4 (0.55) | PRMT5EGFRPIK3CAMLKLCHEK2 | |
| SCHEMBL10102375 | 0.72 | KDM4E (0.43) | EGFRPIK3CASMN1; SMN2HPGDLMNA | |
| SCHEMBL1568740 | 0.72 | CYP19A1 (0.47) | LMNA | |
| SCHEMBL7325948 | 0.72 | CA1 (0.41) | — | |
| SCHEMBL1363970 | 0.70 | DYRK3 (0.54) | HPGD | |
| Hydrochloric Acid SCHEMBL8635004 | 0.70 | MLKL (0.47) | PRMT5EGFRPIK3CAMLKLCHEK2 | |
| SCHEMBL8871162 | 0.69 | SLC6A2 (0.55) | EGFRPIK3CAMLKLPTGS2 | |
| SCHEMBL477559 | 0.67 | UGT2B7 (0.61) | UGT2B7TSHR | |
| SCHEMBL30161628 | 0.67 | UGT2B7 (0.61) | UGT2B7TSHR | |
| SCHEMBL477557 | 0.67 | UGT2B7 (0.61) | UGT2B7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674619-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014770-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |