Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30161628 | 1.00 | UGT2B7 (0.61) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL477557 | 1.00 | UGT2B7 (0.61) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL12405817 | 0.94 | UGT2B7 (0.53) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL30033673 | 0.93 | UGT2B7 (0.68) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL600527 | 0.93 | UGT2B7 (0.68) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL26326669 | 0.90 | UGT2B7 (0.55) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL26326655 | 0.86 | UGT2B7 (0.55) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL14033733 | 0.86 | UGT2B7 (0.55) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL26326654 | 0.86 | UGT2B7 (0.60) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL17064763 | 0.84 | UGT2B7 (0.53) | UGT2B7SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310067-A1 | METHOD FOR PRODUCING ORGANIC METAL NUCLEOPHILIC AGENT AND REACTION METHOD USING ORGANIC METAL NUCLEOPHILIC AGENT | National University Corporation Hokkaido University (JP) | 2024-01-24 | — | — | EP | disclosed |
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
| WO-2022196796-A1 | METHOD FOR PRODUCING ORGANIC METAL NUCLEOPHILIC AGENT AND REACTION METHOD USING ORGANIC METAL NUCLEOPHILIC AGENT | 国立大学法人北海道大学 | 2022-09-22 | — | — | WO | disclosed |
| CN-110922427-B | Process for preparing substituted diphosphonites with bulky steric hindrance | 温州大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-113105409-A | 2- (hydroxybenzyl) benzo [ d ] isothiazolone compound, preparation method and application thereof | 四川大学 | 2021-07-13 | — | — | CN | disclosed |
| WO-2021093556-A1 | METHOD FOR PREPARING HYDROXYL COMPOUND, DEUTERATED COMPOUND THEREOF, AND TRITIATED COMPOUND THEREOF | 中国科学院福建物质结构研究所 | 2021-05-20 | — | — | WO | disclosed |
| CN-110922427-A | Process for preparing diester of large steric hindrance alkyl substituted phosphonite | 温州大学 | 2020-03-27 | — | — | CN | disclosed |
| EP-2380567-B1 | MELANIN PRODUCTION INHIBITOR | POLA CHEM IND INC (JP) | 2019-01-16 | — | — | EP | disclosed |
| EP-3009123-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2016-04-20 | — | — | EP | disclosed |
| EP-2074090-A1 | VINYLOGOUS ACIDS DERIVATIVES AS CHYMASE INHIBITORS | F. Hoffmann-Roche AG (CH) | 2009-07-01 | — | — | EP | disclosed |
| US-20080096953-A1 | Vinylogous acid derivatives | HOFFMANN-LA ROCHE INC. | 2008-04-24 | — | — | US | disclosed |
| WO-2008043698-A1 | VINYLOGOUS ACIDS DERIVATIVES AS CHYMASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-17 | — | — | WO | disclosed |
| US-6417213-B2 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-09 | — | — | US | disclosed |
| US-20020006944-A1 | Tricyclic compounds, their production and use | OHKAWA SHIGENORI (JP) | 2002-01-17 | — | — | US | disclosed |
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| US-4303632-A | Preparation of hydrogen peroxide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| US-4302435-A | Hydrogenation of a diarylketone to a diarylmethanol | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-11-24 | — | — | US | disclosed |
| US-4276305-A | INSECTICIDES, MITICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-06-30 | — | — | US | disclosed |
| EP-0014455-A2 | Cyclopropane(thiol)carboxylic-acid esters, processes for their preparation, pesticides containing such compounds and the use of such compounds as pesticides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096953-A1 | Vinylogous acid derivatives | CMA1, TPSG1, GAA | UGT2B7 742/4885SLC6A2 2772/4885SLC6A4 3257/4885 |
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | HPD, TALDO1, OGG1 | UGT2B7 300/4885SLC6A2 4398/4885SLC6A4 4230/4885 |
| US-20020006944-A1 | Tricyclic compounds, their production and use | CNR1, PTGER1, PTGDR | UGT2B7 837/4885SLC6A2 2988/4885SLC6A4 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.