Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.44 |
| ▸ | DHCR7 | Q9UBM7 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9214060 | 0.94 | DHCR7 (0.48) | KDM2BDHCR7HRH3ABCB1MEN1 | |
| SCHEMBL9211782 | 0.89 | DHCR7 (0.51) | KDM2BDHCR7ABCB1KDM4ETDP1 | |
| SCHEMBL9205910 | 0.85 | DHCR7 (0.57) | DHCR7ABCB1MEN1KMT2AKDM4E | |
| SCHEMBL9207330 | 0.85 | KDM2B (0.41) | KDM2BABCB1MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL9208175 | 0.84 | DHCR7 (0.56) | DHCR7ABCB1MEN1KMT2AKDM4E | |
| SCHEMBL9207036 | 0.84 | HRH3 (0.50) | HRH3ABCB1MEN1KMT2A | |
| SCHEMBL9215721 | 0.84 | KDM2B (0.41) | KDM2BABCB1MEN1KMT2AGAA | |
| SCHEMBL9214620 | 0.84 | ABCB1 (0.52) | DHCR7HRH3ABCB1 | |
| SCHEMBL9213303 | 0.84 | MEN1 (0.49) | KDM2BDHCR7HRH3ABCB1MEN1 | |
| SCHEMBL9213630 | 0.83 | ABCB1 (0.53) | DHCR7HRH3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |