SCHEMBL9211809

SCHEMBL9211809

CC(=O)N(O)C(C)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.69
MTOR P42345 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9707327 0.89 ALOX5 (0.56) ALOX5
SCHEMBL117598 0.85 ALOX5 (0.71) ALOX5MTOR
SCHEMBL9376883 0.84 ALOX5 (0.51) ALOX5
SCHEMBL9376877 0.84 ALOX5 (0.51) ALOX5
SCHEMBL9474495 0.84 ALOX5 (0.51) ALOX5
SCHEMBL9195413 0.84 FFAR1 (0.54) ALOX5
SCHEMBL9641680 0.84 ALOX5 (0.77) ALOX5
Ammonia Solution, Strong SCHEMBL9641537 0.83 ALOX5 (0.75) ALOX5
SCHEMBL9641600 0.83 ALOX5 (0.75) ALOX5
SCHEMBL13524545 0.82 ALOX5 (1.00) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0570197-B1 Hydroxylamine derivatives ZENECA LTD (GB) 1995-12-13 EP claimed
EP-0570197-A1 Hydroxylamine derivatives ZENECA LIMITED (GB) 1993-11-18 EP claimed
EP-0570197-B1 Hydroxylamine derivatives ZENECA LTD (GB) 1995-12-13 EP disclosed
EP-0570197-A1 Hydroxylamine derivatives ZENECA LIMITED (GB) 1993-11-18 EP disclosed